Document Detail

Cervical esophageal webs: association with gastroesophageal reflux.
MedLine Citation:
PMID:  11911167     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We investigated whether there is a significant association between cervical esophageal webs and gastroesophageal reflux on pharyngoesophagography. METHODS: We studied 50 patients with cervical esophageal webs on pharyngoesophagrams and 50 control subjects. The control group was matched to the webs group for age, sex, and symptomatology. Patients with cervical esophageal webs and controls were compared to determine the prevalence of gastroesophageal reflux, hiatal hernias, reflux esophagitis, and abnormal esophageal motility. Pearson's chi-square test was used to determine any statistically significant differences in the frequencies of these findings between groups. RESULTS: Thirty-nine (78%) of 50 patients with cervical esophageal webs versus 27 (54%) of 50 patients in the control group had gastroesophageal reflux (p = 0.01). When patients were classified based on degree of gastroesophageal reflux, 22 (44%) of 50 patients with cervical esophageal webs versus 21 (42%) of 50 controls had mild reflux (p = 0.84), whereas 17 (34%) of 50 patients with webs versus six (12%) of 50 controls (p < 0.009) had moderate/marked reflux. Thus, the prevalence of moderate/marked gastroesophageal reflux was significantly greater in patients with webs than in the controls. However, no significant differences were found in the prevalence of mild gastroesophageal reflux, hiatal hernias, reflux esophagitis, or abnormal esophageal motility. CONCLUSION: We found a significant association between cervical esophageal webs and gastroesophageal reflux independent of age, sex, or symptomatology. Radiologists should be aware of this association, so that patients with cervical esophageal webs on pharyngoesophagography are evaluated for gastroesophageal reflux at the time of the barium study or advised to undergo further testing for gastroesophageal reflux disease.
A R Gordon; M S Levine; R O Redfern; S E Rubesin; I Laufer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Abdominal imaging     Volume:  26     ISSN:  0942-8925     ISO Abbreviation:  Abdom Imaging     Publication Date:    2001 Nov-Dec
Date Detail:
Created Date:  2002-03-25     Completed Date:  2002-04-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9303672     Medline TA:  Abdom Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  574-7     Citation Subset:  IM    
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, 19104, USA.
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MeSH Terms
Case-Control Studies
Esophageal Diseases / complications*,  radiography
Esophageal Motility Disorders / epidemiology,  etiology
Gastroesophageal Reflux / epidemiology,  etiology*
Middle Aged

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