| Cervical dysplasia in pregnancy: a multi-institutional evaluation. | |
| | |
MedLine Citation:
|
PMID: 20522409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: This study was undertaken to identify the prognostic indicators associated with postpartum regression of cervical dysplasia diagnosed in pregnancy. STUDY DESIGN: A retrospective cohort study of pregnant women referred for colposcopy from 2004-2007 at four academic centers. RESULTS: One thousand seventy-nine patients were identified. Colposcopic impression by cervical cytology is detailed later in the text. Of patients who underwent biopsy, results correlated with or were less severe than colposcopic impression in 83% with CIN 1 and 56% with CIN 2/3. Fifty-seven percent had follow-up postpartum, with 61% reverting to normal. Resolution of cervical dysplasia was inversely associated with smoking (P = .002). No progression to cancer occurred during pregnancy. CONCLUSION: Colposcopic impression in pregnancy correlated with cervical biopsy results and postpartum colposcopic findings when performed by expert colposcopists. A high proportion of cervical dysplasia regressed postpartum. Cervical biopsies in pregnancy may not be necessary unless invasive cancer is suspected. |
| | |
Authors:
|
Amanda N Fader; Erin K Alward; Amy Niederhauser; Christina Chirico; Jamie L Lesnock; Daniel J Zwiesler; Richard S Guido; Darla J Lofgren; Michael A Gold; Kathleen N Moore |
Related Documents
:
|
15661209 - Does radical trachelectomy influence uterine blood supply? 9003949 - Laser miniconization procedure. 20460189 - Invasive cervical cancer during pregnancy: laparoscopic nodal evaluation before oncolog... 10804489 - Continuous low-dose antibiotics and cerclage for recurrent second-trimester pregnancy l... 17674259 - Dynamic cervical length changes: preliminary observations from 30-minute transvaginal u... 17190989 - Pentasomy 49,xxxxy associated with a chiari type 1 malformation and cervical syrinx. 10798129 - Zinc levels in women and newborns. 22425089 - The impact of varicocelectomy on sperm parameters: a meta-analysis. 1434509 - Prenatal diagnosis of non-ketotic hyperglycinaemia. |
Publication Detail:
|
Type: Evaluation Studies; Journal Article; Multicenter Study; Research Support, N.I.H., Extramural Date: 2010-06-03 |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 203 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-07-27 Completed Date: 2010-08-17 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 113.e1-6 Citation Subset: AIM; IM |
Copyright Information:
|
Copyright (c) 2010 Mosby, Inc. All rights reserved. |
Affiliation:
|
Department of Obstetrics and Gynecology, Greater Baltimore Medical Center/Johns Hopkins Medical Institutions, Baltimore, MD 21204, USA. amandanfader@gmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Academic Medical Centers Adult Age Distribution Biopsy, Needle Cervical Intraepithelial Neoplasia / diagnosis, epidemiology, pathology* Cohort Studies Colposcopy / methods Female Follow-Up Studies Gestational Age Humans Immunohistochemistry Incidence Multivariate Analysis Precancerous Conditions / epidemiology, pathology Pregnancy Pregnancy Complications, Neoplastic / epidemiology*, pathology Pregnancy Outcome* Prenatal Care Probability Proportional Hazards Models Retrospective Studies Risk Assessment Uterine Cervical Dysplasia / diagnosis, epidemiology*, pathology* Uterine Neoplasms / diagnosis, epidemiology, pathology* Vaginal Smears Young Adult |
| Grant Support | |
ID/Acronym/Agency:
|
M01 RR-14467/RR/NCRR NIH HHS; N02-CP-31102/CP/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The outcome of twin reversed arterial perfusion sequence diagnosed in the first trimester.
Next Document: Postoperative pain after laparoscopic and vaginal hysterectomy for benign gynecologic disease: a ran...