Document Detail


Cervical column morphology and craniofacial profiles in monozygotic twins.
MedLine Citation:
PMID:  18251680     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous studies have described the relationships between cervical column morphology and craniofacial morphology. The aims of the present study were to describe cervical column morphology in 38 pairs of adult monozygotic (MZ) twins, and compare craniofacial morphology in twins with fusions with craniofacial morphology in twins without fusion. Visual assessment of cervical column morphology and cephalometric measurements of craniofacial morphology were performed on profile radiographs. In the cervical column, fusion between corpora of the second and third vertebrae was registered as fusion. In the twin group, 8 twin pairs had fusion of the cervical column in both individuals within the pair (sub-group A), 25 pairs had no fusions (subgroup B), and in 5 pairs, cervical column morphology was different within the pair (subgroup C), as one twin had fusion and the other did not. Comparison of craniofacial profiles showed a tendency to increased jaw retrognathia, larger cranial base angle, and larger mandibular inclination in subgroup A than in subgroup B. The same tendency was observed within subgroup C between the individual twins with fusion compared with those without fusion. These results confirm that cervical fusions and craniofacial morphology may be interrelated in twins when analysed on profile radiographs. The study also documents that differences in cervical column morphology can occur in individuals within a pair of MZ twins. It illustrates that differences in craniofacial morphology between individuals within a pair of MZ twins can be associated with cervical fusion.
Authors:
Liselotte Sonnesen; Carsten Pallisgaard; Inger Kjaer
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Twin Study    
Journal Detail:
Title:  Twin research and human genetics : the official journal of the International Society for Twin Studies     Volume:  11     ISSN:  1832-4274     ISO Abbreviation:  -     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-06     Completed Date:  2008-05-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101244624     Medline TA:  Twin Res Hum Genet     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  84-92     Citation Subset:  IM    
Affiliation:
Department of Orthodontics, Institute of Odontology, Faculty of Health Sciences, Copenhagen University, Denmark. lls@odont.ku.dk
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cephalometry
Cervical Vertebrae / anatomy & histology*,  radiography
Face / anatomy & histology*
Female
Humans
Male
Quantitative Trait, Heritable*
Skull / anatomy & histology*,  radiography
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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