| Cervical chordoma in childhood without typical vertebral bony destruction: case report and review of the literature. | |
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MedLine Citation:
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PMID: 19525829 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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STUDY DESIGN: Case report. OBJECTIVE: We present a giant cervical chordoma without typical vertebral bony destruction in an 11-year-old girl. SUMMARY OF BACKGROUND DATA: Chordomas are rare malignant bone tumors that arise at both the cranial and the caudal ends of the axial skeleton, characteristically destroying the bone. Cervical chordomas comprise only 3% to 7% of all chordomas. To our knowledge, there is no case of cervical chordoma in a child, presenting without vertebral body involvement, in English literature. METHODS: Discussion on the patient's clinical, radiologic history, and histopathologic diagnosis of the resected tumor, with a review of the relevant background literature. RESULTS: We report the first case of cervical chordoma in a child without typical vertebral bony destruction, the diagnosis of which was difficult to confirm before and after operation. CONCLUSION: Giant notochordal rest and benign notochordal cell tumors (BNCTs) need to be recognized for differential diagnosis of this atypical chordoma. A long-term follow-up might be necessary for the diagnosis of this nontypical patient. |
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Authors:
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Hua Zhou; Zhongjun Liu; Cuiling Liu; Qingjun Ma; Xiaoguang Liu; Liang Jiang; Feng Wei |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Spine Volume: 34 ISSN: 1528-1159 ISO Abbreviation: Spine Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-15 Completed Date: 2009-09-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7610646 Medline TA: Spine (Phila Pa 1976) Country: United States |
Other Details:
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Languages: eng Pagination: E493-7 Citation Subset: IM |
Affiliation:
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Department of Orthopedics, Peking University Third Hospital, Beijing, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cervical Vertebrae
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radiography Child Chordoma / diagnosis*, metabolism, surgery Female Humans Keratins / analysis S100 Proteins / analysis Spinal Neoplasms / diagnosis*, metabolism, surgery Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/S100 Proteins; 68238-35-7/Keratins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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