Document Detail

Cervical chordoma in childhood without typical vertebral bony destruction: case report and review of the literature.
MedLine Citation:
PMID:  19525829     Owner:  NLM     Status:  MEDLINE    
STUDY DESIGN: Case report. OBJECTIVE: We present a giant cervical chordoma without typical vertebral bony destruction in an 11-year-old girl. SUMMARY OF BACKGROUND DATA: Chordomas are rare malignant bone tumors that arise at both the cranial and the caudal ends of the axial skeleton, characteristically destroying the bone. Cervical chordomas comprise only 3% to 7% of all chordomas. To our knowledge, there is no case of cervical chordoma in a child, presenting without vertebral body involvement, in English literature. METHODS: Discussion on the patient's clinical, radiologic history, and histopathologic diagnosis of the resected tumor, with a review of the relevant background literature. RESULTS: We report the first case of cervical chordoma in a child without typical vertebral bony destruction, the diagnosis of which was difficult to confirm before and after operation. CONCLUSION: Giant notochordal rest and benign notochordal cell tumors (BNCTs) need to be recognized for differential diagnosis of this atypical chordoma. A long-term follow-up might be necessary for the diagnosis of this nontypical patient.
Hua Zhou; Zhongjun Liu; Cuiling Liu; Qingjun Ma; Xiaoguang Liu; Liang Jiang; Feng Wei
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Spine     Volume:  34     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-15     Completed Date:  2009-09-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E493-7     Citation Subset:  IM    
Department of Orthopedics, Peking University Third Hospital, Beijing, China.
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MeSH Terms
Cervical Vertebrae / radiography
Chordoma / diagnosis*,  metabolism,  surgery
Keratins / analysis
S100 Proteins / analysis
Spinal Neoplasms / diagnosis*,  metabolism,  surgery
Treatment Outcome
Reg. No./Substance:
0/S100 Proteins; 68238-35-7/Keratins

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