| Cervical carcinoma and pregnancy. | |
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MedLine Citation:
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PMID: 12731737 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Abortion and conization of the cervix is the treatment of choice for patients with preinvasive cervical carcinoma combined with first-term pregnancy. With the second and third term, the pregnancy is led to delivery and a secondary examination is carried out. In case of preienvasive carcinoma only conization of the cervix is performed. In late-term pregnancy the surgical operation starts with a cesarean section. A combination of cervical carcinoma and pregnancy was observed in 31 (44%) of 6,890 patients admitted to the Gynecological Clinic of the National Cancer Center from 1964-2001. Of 1,911 patients with radical hysterectomy (Stage I--58.4%, Stage II--21.8%, Stage III--20%) a combination of cervical carcinoma and pregnancy was diagnosed in 31 women [Stage I--23 (74.2%), Stage II--4 (12.9%), Stage III--4 (12.9%)]; 93.5% of the patients had a first or second term pregnancy. Five-year survival of the patients with surgery only was 83.3%, while with combined therapy--60%. Twenty-nine percent of the patients were 30 and younger. Pregnancy contributed to early manifestation of cervical cancer and did not favor the aggression of malignant tumor growth. The five-year survival rate of patients without staging and those combined with pregnancy was 72.7%; five-year survival rate of patients with early pregnancy was worse compared to those with second or third term pregnancies. Pregnancy is not a contraindication for performance of radical hysterectomy. |
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Authors:
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L Charkviani; T Charkviani; N Natenadze; Z Tsitsishvili |
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Publication Detail:
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Type: Editorial |
Journal Detail:
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Title: Clinical and experimental obstetrics & gynecology Volume: 30 ISSN: 0390-6663 ISO Abbreviation: Clin Exp Obstet Gynecol Publication Date: 2003 |
Date Detail:
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Created Date: 2003-05-06 Completed Date: 2003-08-12 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802110 Medline TA: Clin Exp Obstet Gynecol Country: Italy |
Other Details:
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Languages: eng Pagination: 19-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carcinoma / epidemiology*, pathology, therapy* Female Georgia (Republic) Humans Hysterectomy Lymphatic Metastasis Neoplasm Staging Postoperative Complications Pregnancy Pregnancy Complications, Neoplastic / epidemiology*, pathology, therapy* Pregnancy Outcome Survival Analysis Uterine Cervical Neoplasms / epidemiology*, pathology, therapy* |
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