Document Detail

Cervical carcinoma in situ associated with azathioprine therapy. A case report and literature review.
MedLine Citation:
PMID:  6391055     Owner:  NLM     Status:  MEDLINE    
The case of a 34-year-old kidney transplant patient who developed carcinoma in situ of the cervix after immunosuppressive therapy with azathioprine is reported. A few case reports and studies of this association have appeared previously in the literature, in addition to many reports associating azathioprine treatment with other malignant tumors. This report reemphasizes this association and the need for close surveillance of patients undergoing immunosuppressive therapy. The pertinent literature on the association of chronic use of immunosuppressive agents with the subsequent development of malignant tumors is briefly reviewed.
I Balachandran; K S Galagan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  28     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1984 Nov-Dec
Date Detail:
Created Date:  1985-01-17     Completed Date:  1985-01-17     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  699-702     Citation Subset:  IM    
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MeSH Terms
Azathioprine / adverse effects*,  therapeutic use
Carcinoma in Situ / chemically induced*,  pathology
Kidney Transplantation*
Methylprednisolone / therapeutic use
Uterine Cervical Dysplasia / chemically induced,  pathology
Uterine Cervical Neoplasms / chemically induced*,  pathology
Vaginal Smears
Reg. No./Substance:
446-86-6/Azathioprine; 83-43-2/Methylprednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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