Document Detail


Cervical cancer associated with pregnancy: results of a multicenter retrospective Korean study (KGOG-1006).
MedLine Citation:
PMID:  17905175     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of the study was to analyze the characteristics of cervical cancer associated with pregnancy. STUDY DESIGN: Forty patients with cervical cancer associated with pregnancy were retrospectively identified between 1995-2003. Three controls for each case were matched on the basis of age, stage, histology, and date of treatment. RESULTS: Sampling of cervical cytology after the second trimester was the most common cause of delayed diagnosis. Among 12 patients who delayed treatment for fetal maturity, 2 died of disease. There was no difference in overall survival between pregnant and nonpregnant patients with stage Ib tumors. In contrast to nonpregnant patients, the depth of stromal invasion was not correlated with the incidence of lymph vascular space involvement and lymph node metastasis in pregnant patients. CONCLUSION: Thorough evaluation is warranted before deciding whether to delay treatment until fetal maturity. Pregnancy does not adversely affect the prognosis of early-stage cervical cancer significantly.
Authors:
Jong-Min Lee; Kwang-Beom Lee; Young-Tak Kim; Hee-Sug Ryu; Young-Tae Kim; Chi-Heum Cho; Sung-Eun Namkoong; Ki-Hun Lee; Ho-Sun Choi; Kyung-Tai Kim
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2007-10-01
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  198     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-01     Completed Date:  2008-01-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  92.e1-6     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, East-West Neo Medical Center, Kyung Hee University, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Case-Control Studies
Combined Modality Therapy
Comorbidity
Female
Gestational Age
Humans
Incidence
Korea / epidemiology
Middle Aged
Neoplasm Staging
Postnatal Care / methods
Pregnancy
Pregnancy Complications, Neoplastic / epidemiology*,  pathology*,  therapy
Pregnancy Outcome*
Prenatal Care / methods
Probability
Prognosis
Reference Values
Retrospective Studies
Risk Assessment
Statistics, Nonparametric
Survival Analysis
Uterine Cervical Neoplasms / epidemiology*,  pathology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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