| Cervical adenocarcinoma in situ recurring as vaginal adenocarcinoma 16 years after hysterectomy. | |
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MedLine Citation:
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PMID: 19620950 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case in which a vaginal adenocarcinoma was discovered in a 67-year-old woman 16 years after hysterectomy for cervical adenocarcinoma in situ. Both the vaginal and cervical lesions exhibited morphologic and immunohistochemical (CDX2-positive) features of intestinal differentiation. Linear array human papillomavirus genotyping demonstrated the vaginal adenocarcinoma to contain human papillomavirus 45. We believe the vaginal adenocarcinoma to be related to the cervical adenocarcinoma in situ and to represent recurrence of this. This is an extremely rare phenomenon with, as far as we are aware, only one previous report in the literature. |
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Authors:
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Daniel P Hurrell; Jackie Jamison; Stephen P Dobbs; W Glenn McCluggage |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists Volume: 28 ISSN: 1538-7151 ISO Abbreviation: Int. J. Gynecol. Pathol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-07-21 Completed Date: 2009-10-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214845 Medline TA: Int J Gynecol Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 296-300 Citation Subset: IM |
Affiliation:
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Department of Pathology, Royal Group of Hospitals, Belfast, Northern Ireland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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metabolism,
pathology*,
virology Aged Cervical Intraepithelial Neoplasia / metabolism, pathology*, virology Female Humans Hysterectomy Immunohistochemistry Neoplasm Recurrence, Local / metabolism, pathology*, virology Papillomavirus Infections / complications Uterine Cervical Neoplasms / metabolism, pathology*, surgery Vaginal Neoplasms / metabolism, pathology*, virology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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