Document Detail


Certain patterns of karyotype evolution in chronic myelogeneous leukaemia. Chromosome abnormalities in CML.
MedLine Citation:
PMID:  1059629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study of chromosome banding pattern of leukaemic cells in 15 patients with CML revealed t(9;22) in all cases. Similar additional chromosome abnormalities were observed in the terminal stage of the disease in 5 of 9 patients with aneuploid cell lines. The most frequent abnormalities were i(17q) and trisomy 8. The regularities of karyotype evolution in the terminal stage of CML are discussed.
Authors:
E L Prigogina; E W Fleischman
Related Documents :
6947929 - The different origin of primary and secondary chromosome aberrations in cancer.
12447959 - Additional chromosomal abnormalities and variability of bcr breakpoints in philadelphia...
3101769 - Bcr-abl rna in patients with chronic myelogenous leukemia.
9730609 - Physical mapping of the t(12;22) translocation breakpoints in a family with a complex t...
7772529 - Familial thrombocytosis.
6091099 - An 8-kilobase abl rna transcript in chronic myelogenous leukemia.
10694689 - Prenatal diagnosis of a fetus with a cryptic translocation 4p;18p and wolf-hirschhorn s...
1113299 - Correlation between balance of specific chromosomes and expression of malignancy in ham...
19761709 - Distal trisomy of 10q with distal monosomy of 15q due to a paternal translocation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Humangenetik     Volume:  30     ISSN:  0018-7348     ISO Abbreviation:  Humangenetik     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-02-27     Completed Date:  1976-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607154     Medline TA:  Humangenetik     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Chromosome Aberrations*
Chromosome Deletion
Chromosomes, Human, 16-18
Chromosomes, Human, 19-20
Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 6-12 and X
Female
Humans
Leukemia, Myeloid / genetics*
Male
Middle Aged
Translocation, Genetic
Trisomy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Tongue pathology and its effect on the stomatognathous system in juvenile cerebral movement disorder...
Next Document:  Radiographic manifestations of malignant mixed uterine tumors.