Document Detail

Certain patterns of karyotype evolution in chronic myelogeneous leukaemia. Chromosome abnormalities in CML.
MedLine Citation:
PMID:  1059629     Owner:  NLM     Status:  MEDLINE    
The study of chromosome banding pattern of leukaemic cells in 15 patients with CML revealed t(9;22) in all cases. Similar additional chromosome abnormalities were observed in the terminal stage of the disease in 5 of 9 patients with aneuploid cell lines. The most frequent abnormalities were i(17q) and trisomy 8. The regularities of karyotype evolution in the terminal stage of CML are discussed.
E L Prigogina; E W Fleischman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Humangenetik     Volume:  30     ISSN:  0018-7348     ISO Abbreviation:  Humangenetik     Publication Date:  1975 Nov 
Date Detail:
Created Date:  1976-02-27     Completed Date:  1976-02-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7607154     Medline TA:  Humangenetik     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  113-9     Citation Subset:  IM    
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MeSH Terms
Chromosome Aberrations*
Chromosome Deletion
Chromosomes, Human, 16-18
Chromosomes, Human, 19-20
Chromosomes, Human, 21-22 and Y
Chromosomes, Human, 6-12 and X
Leukemia, Myeloid / genetics*
Middle Aged
Translocation, Genetic

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