Document Detail


Certain chemical and biological properties of phenol extracts from Listeria monocytogenes.
MedLine Citation:
PMID:  824986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A toxic component obtained by phenol extraction of Listeria monocytogenes 9-125 was found to have a molecular weight of about 2 X 10(6). This material was composed of carbohydrate, protein, lipid, phosphorus, and a component resembling 2-keto-3-deoxyoctanate. Infrared spectrums indicated that similarities existed between this material and Salmonella abortus-equi lipopolysaccharide. Mild acid hydrolysis produced water-soluble and water-insoluble fractions. Sheep erythrocytes sensitized with aqueous phase extracts were agglutinated by antiserums against the whole listerial cells. Further, lethality tests conducted in chicken embryos showed that this component was toxic to them.
Authors:
A R Conklin; I H Siddique
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of veterinary research     Volume:  37     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1976 Nov 
Date Detail:
Created Date:  1976-12-30     Completed Date:  1976-12-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1331-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chick Embryo
Endotoxins / analysis,  isolation & purification*
Hemagglutination Tests
Lipopolysaccharides / analysis
Listeria monocytogenes / analysis*,  immunology
Molecular Weight
Phenols / pharmacology
Salmonella / analysis
Chemical
Reg. No./Substance:
0/Endotoxins; 0/Lipopolysaccharides; 0/Phenols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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