Document Detail


Cerebrovascular responsiveness to hypercapnia in intracerebral tissue transplants.
MedLine Citation:
PMID:  2054653     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Cerebral blood flow was measured using [14C]iodoantipyrine quantitative autoradiography in rats which had previously undergone unilateral ibotenate-induced nucleus basalis lesion followed by intracortical implantation of foetal basal forebrain cell suspensions. Transplants had no effect upon host cortical blood flow, although within the transplant itself, blood flow was significantly lower than the contralateral site. Both the transplant and host cortex exhibited a similar degree of hyperaemia in response to hypercapnia.
Authors:
J Sharkey; D E McBean; P A Kelly
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Brain research     Volume:  542     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-08-01     Completed Date:  1991-08-01     Revised Date:  2009-09-29    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  147-50     Citation Subset:  IM    
Affiliation:
Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Scotland, U.K.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / embryology,  physiopathology*
Cerebrovascular Circulation*
Fetal Tissue Transplantation*
Hypercapnia / physiopathology*
Male
Nerve Tissue / embryology,  transplantation*
Rats
Rats, Inbred Strains
Grant Support
ID/Acronym/Agency:
//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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