Document Detail

Cerebrovascular response to valsalva maneuver: Methodology, normal values, and retest reliability.
MedLine Citation:
PMID:  22565374     Owner:  NLM     Status:  Publisher    
PURPOSE.: To provide reference values of cerebrovascular reactivity measured with transcranial Doppler ultrasonography in response to rapid changes in blood pressure during the late straining phase (IIb) of a Valsalva maneuver (VM). METHODS.: Middle cerebral artery blood flow velocity, arterial blood pressure changes, and end-tidal partial carbon dioxide pressure (pCO(2) ) concentrations were simultaneously and noninvasively measured in 60 healthy subjects. Centro-peripheral Valsalva ratio was calculated by the quotient of cerebrovascular reactivity and peripheral arterial blood pressure response to VM during phase IIb. Age dependency and short- and long-term reliability of indices were evaluated. Correlation between the autonomic response and changes of pCO(2) was calculated. RESULTS.: Centro-peripheral Valsalva ratio was higher in younger healthy subjects, whereas peripheral autonomic reactivity appeared age-independent. There was no correlation between dynamic autoregulatory response and pCO(2) . Short- and long-term measurements of autoregulatory indices showed excellent reliability. CONCLUSIONS.: VM is a suitable maneuver to evaluate dynamic autonomic response using transcranial Doppler ultrasonography and noninvasive arterial blood pressure monitoring. Autonomic response during VM does not depend on pCO(2) . Normal human subjects show age-dependent centro-peripheral autoregulatory response. 2012 Wiley Periodicals, © Inc. J Clin Ultrasound, 2012.
Thomas-Martin Wallasch; Peter Kropp
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-7
Journal Detail:
Title:  Journal of clinical ultrasound : JCU     Volume:  -     ISSN:  1097-0096     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401663     Medline TA:  J Clin Ultrasound     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
MEDAS Ostschweiz, Interdisciplinary Medicine, Kornhausstr. 3, 9000 St. Gallen, Switzerland.
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