Document Detail

Cerebrovascular complications of streptokinase infusion.
MedLine Citation:
PMID:  3974059     Owner:  NLM     Status:  MEDLINE    
Ninety-one patients treated with streptokinase for vascular occlusion were studied retrospectively to document the incidence of cerebral hemorrhage. Three cerebrovascular complications occurred. Two patients had cerebral hemorrhage, one following limb ischemia, the other after acute myocardial infarction. The third patient received streptokinase for an occluded right subclavian bypass graft and suffered a right frontoparietal infarction, presumably secondary to retrograde embolization, but not angiographically proved. This incidence of cerebrovascular complications must be taken within the framework of the baseline incidence following systemic ischemia, but suggests that caution be exercised with this therapy.
M S Aldrich; S A Sherman; H S Greenberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JAMA     Volume:  253     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:    1985 Mar 22-29
Date Detail:
Created Date:  1985-04-04     Completed Date:  1985-04-04     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1777-9     Citation Subset:  AIM; IM    
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MeSH Terms
Arm / blood supply
Cerebral Hemorrhage / chemically induced*,  radiography
Cerebrovascular Disorders / chemically induced*,  radiography
Coronary Vessels
Infusions, Parenteral
Middle Aged
Myocardial Infarction / drug therapy
Retrospective Studies
Streptokinase / administration & dosage,  adverse effects*
Tomography, X-Ray Computed
Reg. No./Substance:
EC 3.4.-/Streptokinase

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