Document Detail

Cerebrovascular Mechanical Properties and Slow Waves of Intracranial Pressure in TBI Patients.
MedLine Citation:
PMID:  21507769     Owner:  NLM     Status:  Publisher    
Myogenic autoregulation of cerebral blood ow is one of the mechanisms affecting cerebral hemodynamics. Short or long-lasting changes in intracranial pressure are believed to reveal the responses of the cerebral system to myogenic stimuli. Through the incorporation of a theoretical model into the experimental measurements of cerebrovascular distensibility and compliance in patients with traumatic brain injury, the current study is an attempt to explain intracranial pressure dynamics in either presence or absence of cerebral autoregulation. The pulse wave velocity and transfer function between arterial blood pressure and intracranial pressure were utilized as the major tools to reect variations in the mechanical properties of distant cerebral artries/arteriols. The results imply that different states of cerebral autoregulation and associated regimes within the cerebrovascular system can lead to different types of interrelationship between the slow variations of intracranial pressure, cerebral arterial distensibility and compliance. Consequently, each of these classes may require different types of treatment on patients with traumatic brain injury.
S Shahsavari; T McKelvey; C Eriksson-Ritze; B Rydenhag
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-15
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  -     ISSN:  1558-2531     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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