Document Detail


Cerebrovascular CO2 reactivity in migraine with aura and without aura. A transcranial Doppler study.
MedLine Citation:
PMID:  7484067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: We studied by means of Transcranial Doppler (TCD) recordings the CO2 cerebrovascular reactivity in migraine patients during the headache-free period. MATERIAL & METHODS: In three groups of subjects (15 controls, 15 suffering from migraine with aura and 15 from migraine without aura) the middle cerebral artery (MCA) mean flow velocity (MFV) was recorded under basal condition and hypocapnia induced by hyperventilation. Relative MFV, PI (Pulsatility Index) changes and Reactivity Index (RI) were calculated. RESULTS: Reactivity Index values were: 0.019 +/- 0.007 (mean +/- SD) in control subjects: 0.029 +/- 0.008 in migraine with aura; 0.022 +/- 0.008 in migraine without aura. Statistical analysis showed a significantly (P < 0.05) increased RI in migraine with aura group. CONCLUSION: Cerebrosvascular CO2 reactivity is increased during the interictal period in migraine with aura patients.
Authors:
G Fiermonte; F Pierelli; F Pauri; F I Cosentino; R Soccorsi; P Giacomini
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  92     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-12-12     Completed Date:  1995-12-12     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  166-9     Citation Subset:  IM    
Affiliation:
Istituto di Clinica delle Malattie Nervose e Mentali, Universit? degli Studi di Roma, La Sapienza, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adult
Brain / blood supply*,  physiopathology
Carbon Dioxide / analysis*
Echoencephalography
Female
Humans
Hypocapnia
Male
Migraine Disorders / diagnosis*,  physiopathology
Regional Blood Flow
Ultrasonography, Doppler, Transcranial*
Chemical
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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