Document Detail

Cerebrospinal fluid variables among alcoholics lack seasonal variation.
MedLine Citation:
PMID:  1724338     Owner:  NLM     Status:  MEDLINE    
Seasonal influences on indices of serotonergic function, including cerebrospinal fluid (CSF) concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA), have been reported in psychiatric patients and healthy volunteers. We examined seasonal differences in CSF concentrations of 5-HIAA among 135 alcoholics admitted to a research ward who had a lumbar puncture. No significant seasonal differences were found for either CSF concentrations of 5-HIAA or CSF concentrations of other monoamine metabolites or peptides. The possible explanations for these negative findings are discussed.
A Roy; B Adinoff; J DeJong; M Linnoila
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta psychiatrica Scandinavica     Volume:  84     ISSN:  0001-690X     ISO Abbreviation:  Acta Psychiatr Scand     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-04-01     Completed Date:  1992-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370364     Medline TA:  Acta Psychiatr Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  579-82     Citation Subset:  IM    
Laboratory of Clinical Studies, DICBR, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland.
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MeSH Terms
Alcoholism / cerebrospinal fluid*,  rehabilitation
Homovanillic Acid / cerebrospinal fluid
Hydroxyindoleacetic Acid / cerebrospinal fluid*
Methoxyhydroxyphenylglycol / cerebrospinal fluid
Middle Aged
Neuropeptides / cerebrospinal fluid*
Norepinephrine / cerebrospinal fluid
Serotonin / physiology*
Substance Abuse Treatment Centers
Reg. No./Substance:
0/Neuropeptides; 306-08-1/Homovanillic Acid; 50-67-9/Serotonin; 51-41-2/Norepinephrine; 534-82-7/Methoxyhydroxyphenylglycol; 54-16-0/Hydroxyindoleacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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