Document Detail

Cerebrospinal fluid and serum levels of albumin, IgG, IgA and IgM in patients with intracranial tumors and lumbar disc herniation.
MedLine Citation:
PMID:  3595664     Owner:  NLM     Status:  MEDLINE    
CSF and serum albumin, immunoglobulin (Ig) G, IgA and IgM were measured in 100 patients with intracranial tumors, 79 with lumbar disc herniation and 68 free of neurologic diseases. Increases in one or more of the CSF Igs were observed in 46% of the patients with lumbar disc herniation and in 77% of those with intracranial tumors. The CSF-serum protein distribution suggested that impairment of the blood-brain barrier and CNS synthesis of IgG occurred in 15 and 8% of the patients with lumbar disc herniation, respectively; the proportions of tumor patients were 12 and 22%.
M L Rao; D K Böker
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European neurology     Volume:  26     ISSN:  0014-3022     ISO Abbreviation:  Eur. Neurol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-08-07     Completed Date:  1987-08-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  241-5     Citation Subset:  IM    
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MeSH Terms
Albumins / analysis*
Blood-Brain Barrier*
Brain Neoplasms / analysis*
Immunoglobulin A / analysis
Immunoglobulin G / analysis
Immunoglobulin M / analysis
Immunoglobulins / analysis*
Intervertebral Disk Displacement / blood,  cerebrospinal fluid*
Lumbar Vertebrae
Middle Aged
Reg. No./Substance:
0/Albumins; 0/Immunoglobulin A; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulins

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