| Cerebrospinal fluid neuron-specific enolase is decreased in multi-infarct dementia, but unchanged in Alzheimer's disease. | |
| | |
MedLine Citation:
|
PMID: 3379429 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cerebrospinal fluid (CSF) levels of neuron-specific enolase (NSE) were measured in 22 patients with probable Alzheimer's disease and in 35 patients with multi-infarct dementia, and in 15 controls. CSF NSE in patients with Alzheimer's disease did not differ from those in controls. In patients with multi-infarct dementia without recent vascular events CSF NSE was lower than in controls or in Alzheimer patients. This finding is in accord with the prevailing opinion that vascular dementia is caused by multiple infarcts and not by continuous neuronal ischaemia. |
| | |
Authors:
|
R Sulkava; L Viinikka; T Erkinjuntti; R Roine |
Related Documents
:
|
19786779 - Evaluation of cerebrospinal fluid tau/beta-amyloid(42) ratio as diagnostic markers for ... 8507819 - Advance directives are associated with "good deaths" in chronic dialysis patients. 20491609 - Effect of brain-derived neurotrophic factor val66met polymorphism and serum levels on t... 1141629 - The brain ganglioside pattern in presenile and senile dementia. 12819409 - A metabolic imaging severity rating scale for the assessment of cognitive impairment. 1527229 - Debrisoquine hydroxylation phenotypes of patients with high versus low to normal serum ... 2181269 - Clinical autonomic neuropharmacology. 6123489 - Prolactin secretion response to trh stimulation in acute and chronic schizophrenic pati... 22341669 - Recurrent left atrial myxomas in carney complex: a genetic cause of multiple strokes th... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of neurology, neurosurgery, and psychiatry Volume: 51 ISSN: 0022-3050 ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 1988 Apr |
Date Detail:
|
Created Date: 1988-07-15 Completed Date: 1988-07-15 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 549-51 Citation Subset: IM |
Affiliation:
|
Department of Neurology, University of Helsinki, Finland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Alzheimer Disease / enzymology*, pathology Brain / pathology Dementia / enzymology*, pathology Female Humans Male Middle Aged Phosphopyruvate Hydratase / cerebrospinal fluid* Radioimmunoassay |
| Chemical | |
Reg. No./Substance:
|
EC 4.2.1.11/Phosphopyruvate Hydratase |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The pedunculopontine nucleus in Parkinson's disease, progressive supranuclear palsy and Alzheimer's ...
Next Document: Painful muscle spasms complicating algodystrophy: central or peripheral disease?