Document Detail


Cerebrospinal fluid leakage, an uncommon complication of fetal blood sampling: a case report and review of the literature.
MedLine Citation:
PMID:  21510911     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In a recently published randomized clinical trial on intrapartum fetal monitoring, fetal blood samples were obtained in 879 women. One serious complication of fetal blood sampling (FBS) was reported, a case in which physical examination of the neonate after delivery revealed clear fluid loss from the incision site. Four layers of the scalp appeared to be incised. The subarachnoid space was closed with 2 sutures, and antibiotics were started due to the risk of meningitis. The patient was discharged in good clinical condition. In this article, the case is presented and the literature reviewed. We found 12 articles reporting 37 cases of a complication due to FBS, none concerning leakage of cerebrospinal fluid. In conclusion, complications of FBS are rare but can be serious. Excessive fetal bleeding is most frequently reported and often associated with an underlying coagulopathy in the neonate. Target Audience: Obstetricians & Gynecologists, Family Physicians Learning Objectives: After completion of this educational activity, the obstetrician/gynecologist should be better able to assess the chance of possible complications due to fetal blood sampling; select fetuses at risk for complications due to fetal blood sampling; and evaluate certain technical precautions when performing this procedure.
Authors:
Timme P Schaap; Karlijn A Moormann; Jeroen H Becker; Michelle E M H Westerhuis; Annemieke Evers; Hens A A Brouwers; Nico W E Schuitemaker; Gerard H A Visser; Anneke Kwee
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrical & gynecological survey     Volume:  66     ISSN:  1533-9866     ISO Abbreviation:  Obstet Gynecol Surv     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401007     Medline TA:  Obstet Gynecol Surv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  42-6     Citation Subset:  IM    
Affiliation:
*Physician, †Obstetrician, Department of Obstetrics and Gynecology, Diakonessenhuis Utrecht, Utrecht, the Netherlands; ‡Physician, §Professor in Obstetrics, ¶Obstetrician, Department of Perinatology and Gynecology, University Medical Center Utrecht, Utrecht, the Netherlands; and ‡Neonatologist, Department of Neonatology, University Medical Center Utrecht, Utrecht, the Netherlands.
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