| Cerebrospinal fluid insulin during non-neurological surgery. | |
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MedLine Citation:
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PMID: 20697751 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Insulin plays an important metabolic and transmitter role in the central nervous system, but few studies have investigated the relationship between central and peripheral insulin concentrations. 35 patients undergoing knee surgery had cerebrospinal fluid (CSF) samples drawn before, 3 h after, and in the morning following surgery. Serum insulin concentrations increased after surgery and CSF insulin concentrations changed in the same direction with far smaller amplitude. These results indicate that the blood-brain barrier protects the brain from stress-induced peripheral hormonal fluctuations. |
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Authors:
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Sara Bromander; Rolf Anckarsäter; Bo Ahrén; Marianne Kristiansson; Kaj Blennow; Agneta Holmäng; Henrik Zetterberg; Henrik Anckarsäter; Caroline E Wass |
Publication Detail:
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Type: Journal Article Date: 2010-08-10 |
Journal Detail:
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Title: Journal of neural transmission (Vienna, Austria : 1996) Volume: 117 ISSN: 1435-1463 ISO Abbreviation: J Neural Transm Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9702341 Medline TA: J Neural Transm Country: Austria |
Other Details:
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Languages: eng Pagination: 1167-70 Citation Subset: IM |
Affiliation:
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Forensic Psychiatry, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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