Document Detail


Cerebrospinal fluid ferritin in patients with leukaemia and malignant lymphoma.
MedLine Citation:
PMID:  3863234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate whether cerebrospinal fluid (CSF) ferritin could be of diagnostic value in haematological malignancies with central nervous system (CNS) involvement, the ferritin concentration was measured in 21 patients with acute leukaemia and lymphoma. Of the 17 patients without CNS involvement, 16 had CSF ferritin values in the normal range (2-7 micrograms/l); 1 patient had an elevated value, probably due to blood contamination in connection with a very high serum ferritin level. 4 patients had tumour invasion of the CNS indicated by the presence of blastic cells in the CSF; CSF ferritin levels in these patients were likewise in the normal range. There was no difference between CSF ferritin values in patients with and without CNS involvement. With the present assay, measurement of CSF ferritin appears to be irrelevant in the evaluation of CNS invasion in haematological malignancies.
Authors:
N Milman; L Vig; N S Pedersen; T S Olsen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of haematology     Volume:  35     ISSN:  0036-553X     ISO Abbreviation:  Scand J Haematol     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-20     Completed Date:  1985-11-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404507     Medline TA:  Scand J Haematol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  132-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Brain Neoplasms / blood,  cerebrospinal fluid
Female
Ferritins / blood,  cerebrospinal fluid*
Humans
Leukemia, Lymphoid / cerebrospinal fluid*
Leukemia, Myeloid, Acute / cerebrospinal fluid*
Lymphoma / cerebrospinal fluid*
Male
Middle Aged
Serum Albumin / analysis
Chemical
Reg. No./Substance:
0/Serum Albumin; 9007-73-2/Ferritins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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