Document Detail

Cerebrospinal fluid content of manganese, platinum, and strontium in patients with cerebral tumors, leukemia, and other noncerebral neoplasms.
MedLine Citation:
PMID:  2216293     Owner:  NLM     Status:  MEDLINE    
Electrothermal atomic absorption spectrophotometry was employed to measure the concentrations of manganese, platinum, and strontium in the cerebrospinal fluid (CSF) of 47 patients with brain neoplasms (34 benign and 13 malignant), 17 leukemic patients, 10 patients with lymphoma or non-cerebral solid tumors, and 27 control patients. According to the data obtained, manganese appears to be significantly (p less than 0.015) depleted from the CSF of leukemic patients, whereas platinum is diminished in CSF of patients with brain tumors, leukemia, lymphoma, or noncerebral solid tumors; the ratios for the mean CSF concentration of platinum in these tumor patients/control patients ranged between 0.52 and 0.7. There was no significant difference in CSF concentrations of strontium among the groups examined.
A el-Yazigi; I Kanaan; C R Martin; E B Siqueira
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oncology     Volume:  47     ISSN:  0030-2414     ISO Abbreviation:  Oncology     Publication Date:  1990  
Date Detail:
Created Date:  1990-10-31     Completed Date:  1990-10-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0135054     Medline TA:  Oncology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  385-8     Citation Subset:  IM    
Biological and Medical Research Department, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
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MeSH Terms
Brain Neoplasms / cerebrospinal fluid*
Breast Neoplasms / cerebrospinal fluid*
Lymphoma / cerebrospinal fluid*
Manganese / cerebrospinal fluid*
Platinum / cerebrospinal fluid*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / cerebrospinal fluid*
Reference Values
Sarcoma / cerebrospinal fluid*
Strontium / cerebrospinal fluid*
Reg. No./Substance:
7439-96-5/Manganese; 7440-06-4/Platinum; 7440-24-6/Strontium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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