Document Detail


Cerebriform plantar hyperplasia: ultrastructural study of two cases.
MedLine Citation:
PMID:  11056430     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present work we report the histopathological features of the cerebriform plantar hyperplasia observed in two patients with a mild form of the Proteus syndrome. Light microscopy revealed increased fibro-adipose tissue and adnexal structures in the dermis. Ultrastructurally, densely packed collagen fibrils variable in diameter and configuration, described as composite fibrils and unraveled fibrils, as well as a few fragmented elastic fibrils presenting an altered ratio between the elastin and the microfibrillar components were the major features observed. We consider that these histopathological findings will contribute to further delineate cerebriform plantar hyperplasia and also to establish clues for the early diagnosis of the Proteus syndrome.
Authors:
B C Winik; M C Boente; R A Asial
Publication Detail:
Type:  Case Reports; Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of dermatology : EJD     Volume:  10     ISSN:  1167-1122     ISO Abbreviation:  Eur J Dermatol     Publication Date:    2000 Oct-Nov
Date Detail:
Created Date:  2000-12-13     Completed Date:  2000-12-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9206420     Medline TA:  Eur J Dermatol     Country:  FRANCE    
Other Details:
Languages:  eng     Pagination:  551-4     Citation Subset:  IM    
Affiliation:
Department of Electron microscopy, INSIBIO, CONICET, Universidad Nacional de Tucumán, Tucumán, Argentina. lamenoa@unt.edu.ar
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / ultrastructure*
Biopsy, Needle
Child
Child, Preschool
Collagen / ultrastructure*
Culture Techniques
Foot
Humans
Hyperplasia
Proteus Syndrome / pathology*
Reference Values
Skin / pathology*
Sweat Glands / ultrastructure
Chemical
Reg. No./Substance:
9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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