Document Detail


Cerebral ventricular dilation in congenital myotonic dystrophy.
MedLine Citation:
PMID:  3305848     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ultrasonography or computed tomography scanning of the brain was performed in 10 infants with congenital myotonic dystrophy between the age of 1 day and 2 months, and showed intracranial abnormalities in all. Ventricular dilation was diagnosed in eight (80%), subarachnoid hemorrhage in one, and white matter infarcts in one. The common finding of ventricular dilation is probably related to developmental brain abnormality dating back to fetal life, because it was already present in three infants scanned on the first day of life. Neonatal asphyxia was present in seven infants, associated with intraventricular hemorrhage in two. The relationship between these changes and mental retardation, which is a common feature in this disease, is unclear.
Authors:
R Regev; L S de Vries; J Z Heckmatt; V Dubowitz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  111     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-10-05     Completed Date:  1987-10-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  372-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Cerebral Ventricles / abnormalities*
Dilatation, Pathologic / pathology
Humans
Infant
Infant, Newborn
Myotonic Dystrophy / congenital*,  pathology
Subarachnoid Hemorrhage / pathology
Tomography, X-Ray Computed
Ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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