Document Detail


Cerebral venous thrombosis in a patient with Evans syndrome: a rare association.
MedLine Citation:
PMID:  15526099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In this report we describe a case of extensive cerebral venous thrombosis in a patient with Evans syndrome. A 19-year-old male patient with Evans syndrome was admitted to the hospital with the complaints of headache, convulsive seizure, and vomiting. The cerebral venous thrombosis including left lateral, left sigmoid, straight sinus, and vena jugularis interna was diagnosed by cerebral magnetic resonance angiography. When the thrombosis developed, he was in hematological remission and he was not receiving any medications except lamivudine for chronic hepatitis B infection. As a genetic prothrombotic risk factor, he had heterozygous prothrombin G20210A gene mutation. His clinical and radiologic findings improved after unfractionated heparin and subsequently with coumadin therapy. On follow-up, cerebral venous thrombosis reoccurred in different localizations, but complete recanalization could be obtained with antithrombotic therapy. We present the case since the association of cerebral venous thrombosis and Evans syndrome is very rare.
Authors:
Sebnem Yilmaz; Hale Oren; Gülersu Irken; Meral Türker; Ebru Yilmaz; Emel Ada
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Publication Detail:
Type:  Case Reports; Letter; Review     Date:  2004-10-30
Journal Detail:
Title:  Annals of hematology     Volume:  84     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-03-07     Completed Date:  2005-05-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  124-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Anemia, Hemolytic, Autoimmune / complications*
Humans
Intracranial Thrombosis / etiology*,  therapy
Male
Point Mutation
Prothrombin / genetics
Syndrome
Venous Thrombosis / etiology*,  therapy
Chemical
Reg. No./Substance:
9001-26-7/Prothrombin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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