Document Detail


Cerebral venous thrombosis: clinical outcome and systematic screening of prothrombotic factors.
MedLine Citation:
PMID:  12682328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The authors studied 16 consecutive cases of cerebral venous thrombosis (CVT). Clinical outcome was good or excellent in 14 patients. Comprehensive hypercoagulable screening was done at least 3 months after the onset of CVT, including evaluation of genetic coagulation disorders and plasma levels of homocysteine and factor VIII. This screening was positive in 12 patients (75%). An acquired prothrombotic factor was identified in 9 of these 12 patients. Elevation of factor VIII plasma level was the most common coagulation disorder (8 patients).
Authors:
S Cakmak; L Derex; M Berruyer; N Nighoghossian; F Philippeau; P Adeleine; M Hermier; J C Froment; P Trouillas
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  60     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-08     Completed Date:  2003-04-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1175-8     Citation Subset:  AIM; IM    
Affiliation:
Service d'Urgences Neurovasculaires, Hôpital Neurologique, Lyon, France.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / therapeutic use
Cerebral Angiography
Disability Evaluation
Factor VIII / analysis
Female
Heparin / therapeutic use
Homocysteine / blood
Humans
Intracranial Thrombosis / diagnosis*,  etiology*,  therapy
Magnetic Resonance Angiography
Magnetic Resonance Imaging
Male
Mass Screening
Thrombophilia / complications*,  diagnosis*,  drug therapy
Time Factors
Treatment Outcome
Chemical
Reg. No./Substance:
0/Anticoagulants; 454-28-4/Homocysteine; 9001-27-8/Factor VIII; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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