Document Detail

Cerebral vein thrombosis in childhood systemic lupus erythematosus.
MedLine Citation:
PMID:  7751995     Owner:  NLM     Status:  MEDLINE    
We describe three cases of cerebral vein thrombosis (CVT) in girls with systemic lupus erythematosus. Severe, persistent, unremitting headache was a common manifestation. In the first patient, although the clinical features were suggestive of CVT, the diagnosis was delayed and she had a significant cerebral infarct. In the other two patients the diagnosis was made earlier and led to more rapid treatment; the institution of early therapy may have prevented further sequelae. The CVT was diagnosed in all patients with a combination of computed tomography and magnetic resonance imaging studies without the need for angiography. All patients were treated for their underlying systemic lupus erythematosus and with anticoagulation. All are receiving long-term low doses of warfarin and have not had any recurrences.
Y Uziel; R M Laxer; S Blaser; M Andrew; R Schneider; E D Silverman
Related Documents :
20884345 - Identification of α-tubulin as an autoantigen recognized by sera from patients with ne...
8554655 - Neurologic manifestations of pediatric systemic lupus erythematosus.
20975635 - Cardiovascular risk profile in systemic lupus erythematosus and rheumatoid arthritis: a...
2787955 - Antinuclear antibodies in patients with chronic idiopathic autoimmune thrombocytopenia ...
10919425 - Translaryngeal tracheostomy in highly unstable patients.
22242085 - Persistently elevated iga antibodies to mycoplasma pneumoniae in patients with internal...
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  126     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-06-19     Completed Date:  1995-06-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  722-7     Citation Subset:  AIM; IM    
Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antibodies, Antinuclear / blood
Anticoagulants / therapeutic use
Follow-Up Studies
Headache / etiology
Intracranial Embolism and Thrombosis / blood,  diagnosis,  etiology*,  prevention & control
Lupus Erythematosus, Systemic / blood,  complications*,  diagnosis,  drug therapy
Magnetic Resonance Imaging
Time Factors
Tomography, X-Ray Computed
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Anticoagulants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Long-term efficacy of recombinant hepatitis B vaccine and risk of natural infection in infants born ...
Next Document:  Low-density lipoprotein apheresis as long-term treatment for children with homozygous familial hyper...