Document Detail


Cerebral vein thrombosis in childhood systemic lupus erythematosus.
MedLine Citation:
PMID:  7751995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe three cases of cerebral vein thrombosis (CVT) in girls with systemic lupus erythematosus. Severe, persistent, unremitting headache was a common manifestation. In the first patient, although the clinical features were suggestive of CVT, the diagnosis was delayed and she had a significant cerebral infarct. In the other two patients the diagnosis was made earlier and led to more rapid treatment; the institution of early therapy may have prevented further sequelae. The CVT was diagnosed in all patients with a combination of computed tomography and magnetic resonance imaging studies without the need for angiography. All patients were treated for their underlying systemic lupus erythematosus and with anticoagulation. All are receiving long-term low doses of warfarin and have not had any recurrences.
Authors:
Y Uziel; R M Laxer; S Blaser; M Andrew; R Schneider; E D Silverman
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  126     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-06-19     Completed Date:  1995-06-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  722-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Antibodies, Antinuclear / blood
Anticoagulants / therapeutic use
Child
Female
Follow-Up Studies
Headache / etiology
Humans
Intracranial Embolism and Thrombosis / blood,  diagnosis,  etiology*,  prevention & control
Lupus Erythematosus, Systemic / blood,  complications*,  diagnosis,  drug therapy
Magnetic Resonance Imaging
Time Factors
Tomography, X-Ray Computed
Chemical
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Anticoagulants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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