Document Detail


Cerebral vasoreactivity: a comparison of color velocity imaging quantification and stable xenon-enhanced CT.
MedLine Citation:
PMID:  15728622     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Compromised cerebral vasoreactivity increases the risk of stroke. In this study, we sought to determine whether extracranial arterial blood flow volume measured on color velocity imaging quantification could be predictive of cerebral vasoreactivity after the administration of acetazolamide. SUBJECTS AND METHODS: Cerebral blood flow and extracranial arterial blood flow volume of 35 patients with symptomatic carotid occlusive disease were measured before and after the administration of acetazolamide on stable xenon CT and color velocity imaging quantification, respectively. The changes in unilateral extracranial arterial blood flow volume and respective hemispheric cerebral blood flow were compared. The mean difference in the percentage of change in flow volume, the 95% limit of agreement, and Cohen's kappa coefficient were calculated. RESULTS: A total of 64 unilateral extracranial arterial blood flow volume changes were successfully compared with the changes in the ipsilateral hemispheric cerebral blood flow. The mean difference in percentage of change in flow volume between the two techniques was 4.7%, with the 95% limit of agreement ranging from -90.2% to 99.7%. Cohen's kappa coefficient was 0.41 (95% confidence interval, 0.13-0.68; p = 0.001). CONCLUSION: The performance of color velocity imaging quantification for evaluating cerebral vasoreactivity is comparable to that of transcranial Doppler sonography. Because color velocity imaging quantification is not as limited as transcranial Doppler sonography, it could be an ideal complementary tool to transcranial Doppler sonography. More studies are required to define its clinical value.
Authors:
S S Y Ho; W W-M Lam; S C P Ng; M K Lam; M T V Chan; W S Poon; C Metreweli
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  184     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-24     Completed Date:  2005-04-14     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  948-52     Citation Subset:  AIM; IM    
Affiliation:
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Ngan Shing St., Shatin, New Territories, Hong Kong.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Blood Flow Velocity
Carotid Stenosis / physiopathology*,  radiography*
Cerebrovascular Circulation*
Color
Female
Humans
Male
Middle Aged
Regional Blood Flow
Tomography, X-Ray Computed* / methods
Vasodilation*
Xenon / diagnostic use*
Chemical
Reg. No./Substance:
7440-63-3/Xenon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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