| Cerebral tuberculoma in pregnancy: overview of the literature and report of a case. | |
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MedLine Citation:
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PMID: 21425075 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Tubercle bacilli infect about one third of the world's population and over the past decade resurgence of tuberculosis has been a major health threat mainly due to increasing frequencies of immunosuppressive states and drug-resistant organisms. Although tuberculosis is essentially a lung disease, intracranial elements become involved in 5-10% of cases either as meningitis or tumour-like masses (tuberculoma). Tuberculoma is common in endemic areas but its occurrence during pregnancy is occasional and of particular interest is its intriguing clinical picture mimicking toxemia of pregnancy and brain tumor. In addition, the effects of pregnancy on tuberculosis or vice versa have been controversial. We present here a review of the recent literature and discuss a case coming to medical attention with manifestations of intracranial hypertension during 2 consecutive pregnancies; 4 years apart. On operation a dura-attached mass was detected that proved to be a tuberculoma. After 18 months of close observation and under drug therapy she obviously improved with no ensuing complication. Immunodeficiency state associated with pregnancy is likely to play a role in activation of infection. Tuberculoma should be considered in differential diagnosis of eclampsia and brain mass particularly in women coming from endemic areas for this infection even in the absence of pulmonary involvement. |
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Authors:
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Seyed Ali Ahmadi; Hadi Roozbeh; Ali Abbasi; Moslem Bahadori; Katayoun Gohari Moghaddam; Seyed Ebrahim Ketabchi |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Acta medica Iranica Volume: 49 ISSN: 1735-9694 ISO Abbreviation: Acta Med Iran Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-22 Completed Date: 2011-07-01 Revised Date: 2011-08-05 |
Medline Journal Info:
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Nlm Unique ID: 14540050R Medline TA: Acta Med Iran Country: Iran |
Other Details:
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Languages: eng Pagination: 64-9 Citation Subset: IM |
Affiliation:
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Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Iran. ahmadise@tums.ac.ir |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain Diseases / complications*, diagnosis Female Humans Magnetic Resonance Imaging Pregnancy Pregnancy Complications, Infectious* / diagnosis Tuberculosis / complications*, diagnosis |
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