Document Detail


Cerebral sinovenous thrombosis in a nephrotic child.
MedLine Citation:
PMID:  14762612     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrotic syndrome in infancy and childhood is known to be associated with a hypercoagulable state and thromboembolic complications, but cerebral sinovenous thrombosis (CST) is a very rare and serious one, with only a few isolated reports in the literature. A case is presented of a 9-year-old boy with nephrotic syndrome that acutely developed signs and symptoms of intracranial hypertension syndrome. CST was diagnosed on cranial CT and MRI and he gradually recovered after treatment with anticoagulants. The diagnosis of CST should be considered in any patient with nephrotic syndrome who develops neurologic symptoms. The discussion of this case, coupled with a review of the literature, emphasizes that early diagnosis is essential for institution of anticoagulation therapy and a successful outcome. This report also illustrates the difficulties that may be encountered in managing such a patient.
Authors:
Marcelo Masruha Rodrigues; Lilian Rocha Zardini; Maria Cristina de Andrade; Cristina Malzoni Ferreira Mangia; João Tomas de Abreu Carvalhaes; Luiz Celso Pereira Vilanova
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2004-01-06
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  61     ISSN:  0004-282X     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-02-05     Completed Date:  2004-06-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  1026-9     Citation Subset:  IM    
Affiliation:
Department of Neurology, Federal University of São Paulo, São Paulo, SP, Brazil. mmasruha@ig.com.br
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MeSH Terms
Descriptor/Qualifier:
Child
Humans
Magnetic Resonance Angiography
Male
Nephrotic Syndrome / complications*,  diagnosis
Phlebography
Radiographic Image Enhancement
Sinus Thrombosis, Intracranial / complications*,  diagnosis
Tomography, X-Ray Computed

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