| Cerebral schistosomiasis japonica without gastrointestinal system involvement. | |
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MedLine Citation:
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PMID: 18207555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Schistosoma japonicum is the most widespread schistosoma in the world. Although gastrointestinal system involvement with S japonicum appears to be considerably common, cerebral schistosomiasis is not frequent. Cerebral schistosomiasis japonica intestinal and hepatosplenic involvement is more rare. We collected 2 cases of cerebral schistosomiasis identified by pathological diagnosis, lacking extracranial involvement. In addition, one of them had multiple lesions, which was also rare. CASE DESCRIPTION: Two male patients came from Dongting Lake region, Hunan province, one of the oldest and most severe endemic areas of China. Their clinical symptoms varied, such as headache, dizziness, seizures, and others. Studies in blood were normal except for eosinophilia. Computed tomography of brains showed hyperdense areas, and MRI showed isointense signal on T1-weighted images, hyperintense signal on T2-weighted images, and heterogeneous enhancement. The definitive diagnosis was cerebral schistosomiasis japonium by biopsy. Standard use of praziquantel and corticosteroid drugs was applied, and the prognosis was good. CONCLUSION: Cerebral schistosomiasis japonica without intestinal and hepatosplenic involvement is exactly rare and easily ignored. The diagnosis sometimes is difficult. Laboratory and imaging examinations are helpful but not specific. Although operation can give the definitive diagnosis, it is not imperative. The administration of praziquantel and corticosteroid drugs in early stages is good for prognosis. |
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Authors:
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Jinxia Zhou; Guoliang Li; Jian Xia; Bo Xiao; Fangfang Bi; Ding Liu; Chanjuan Chen |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-01-22 |
Journal Detail:
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Title: Surgical neurology Volume: 71 ISSN: 0090-3019 ISO Abbreviation: Surg Neurol Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-03-30 Completed Date: 2009-07-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0367070 Medline TA: Surg Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 481-6 Citation Subset: IM |
Affiliation:
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Department of Neurology at Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenal Cortex Hormones / therapeutic use Adult Anthelmintics / therapeutic use Anti-Inflammatory Agents / therapeutic use Brain / parasitology*, pathology, radiography Brain Edema / parasitology, pathology, radiography Diagnosis, Differential Gastrointestinal Tract / parasitology, pathology Humans Magnetic Resonance Imaging Male Neuroschistosomiasis / diagnosis*, drug therapy, parasitology* Praziquantel / therapeutic use Predictive Value of Tests Schistosomiasis japonica / diagnosis*, drug therapy Tomography, X-Ray Computed Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anthelmintics; 0/Anti-Inflammatory Agents; 55268-74-1/Praziquantel |
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