Document Detail

Cerebral salt wasting in a child with cervicothoracic hematoma.
MedLine Citation:
PMID:  18780605     Owner:  NLM     Status:  MEDLINE    
Although the syndrome of inappropriate antidiuretic hormone secretion (SIADH) is commonly observed in patients with acute or chronic central nervous system (CNS) disorders, cerebral salt wasting (CSW) that results in hyponatremia has rarely been reported in children. Both SIADH and CSW result in increased urinary sodium excretion and hyponatremia. However, the management protocols for these two conditions are quite different; volume restriction is used in treating SIADH, while volume expansion is necessary for the treatment of CSW. We present a case of CSW in a child with cervicothoracic hematoma secondary to head and cervicothoracic trauma, without evidence of brain edema. The child was diagnosed on the basis of high urinary sodium excretion resulting in hyponatremia and low serum osmolarity. Improvements in serum sodium levels after saline hydration confirmed this diagnosis. We believe that potentially dangerous cases of hyponatremia should be carefully evaluated in children with cervicothoracic hematoma secondary to trauma, including situations in which brain edema is absent.
Enver Simsek; Dilek Dilli; Ugur Yasitli; Nevin Ozlem; Ilknur Bostanci; Yildiz Dallar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  21     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-09-10     Completed Date:  2008-10-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  695-700     Citation Subset:  IM    
Department of Paediatric Endocrinology, Ministry of Health Ankara Training and Research Hospital, Ankara, Turkey.
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MeSH Terms
Accidents, Traffic
Cervical Vertebrae / injuries*
Extracellular Fluid / physiology
Head Injuries, Closed / complications
Hematoma / complications*,  etiology*
Hyponatremia / etiology*
Magnetic Resonance Imaging
Thoracic Vertebrae / injuries*
Tomography, X-Ray Computed

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