| Cerebral rhinocele, hydrocephalus, and cleft lip and palate in infants with cardiac fibroma. | |
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MedLine Citation:
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PMID: 2250168 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac transplantation was performed in two infants with unresectable fibromas of the myocardium. In one patient, lip surgery was also required for unilateral cleft lip and palate. At autopsy, communicating hydrocephalus of mild to moderate degree was found in both cases. In the patient with facial clefts, there was also a large, ipsilateral cyst, or rhinocele, of the olfactory lobe. This unusual lesion, which seems to represent a previously unreported malformation, was apparently formed by segmental dilatation of a persistent olfactory ventricle. Cerebral or cranial anomalies are thought to be rare in cases of cardiac fibroma; however, macrocephaly was present in five patients. Furthermore, presenting abnormalities among previously reported cases included hydrocephalus in one case, and cleft lip and palate in another. These and other findings suggest that, at least in some cases, cardiac fibroma is a manifestation of a more extensive developmental disorder. |
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Authors:
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G A de León; N Zaeri; R M Donner; N Karmazin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 99 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 1990 Oct |
Date Detail:
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Created Date: 1991-01-15 Completed Date: 1991-01-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 27-36 Citation Subset: IM |
Affiliation:
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Department of Neurology, Temple University School of Medicine, Philadelphia, PA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Brain
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abnormalities* Cleft Lip / complications* Cleft Palate / complications* Female Fibroma / complications* Heart Neoplasms / complications* Humans Infant Tuberous Sclerosis / complications |
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