| Cerebral protection during aneurysm surgery with isoflurane anesthesia. Technical note. | |
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MedLine Citation:
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PMID: 1738037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A strategy for intraoperative cerebral protection is described in which intraoperative electroencephalography is used to titrate the level of inspired isoflurane given for anesthesia to obtain isoelectricity prior to temporary vessel occlusion during repair of difficult aneurysms. During temporary vessel occlusion, arterial blood pressure is maintained or increased with an inotropic or vasopressor agent. After clipping of the aneurysm, the concentration of isoflurane is reduced to allow the patient to awaken in the operating room for early postoperative neurological examination. The combination of a high concentration of isoflurane, temporary vessel occlusion, and maintenance of arterial blood pressure may be a useful protective regimen during neurovascular procedures. |
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Authors:
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F B Meyer; D A Muzzi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of neurosurgery Volume: 76 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 1992 Mar |
Date Detail:
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Created Date: 1992-03-19 Completed Date: 1992-03-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 541-3 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, General
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methods* Brain / drug effects Constriction Electroencephalography / drug effects Female Humans Intracranial Aneurysm / surgery* Isoflurane / administration & dosage* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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26675-46-7/Isoflurane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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