Document Detail


Cerebral plasticity in multiple sclerosis: insights from fMRI.
MedLine Citation:
PMID:  12120689     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Functional magnetic resonance imaging (fMRI) allows noninvasive localization of cerebral activation with relatively high spatial and temporal resolution. The considerable potential for the elucidation of the mechanisms of brain function has made it a useful tool to investigate the neural substrate of motor, sensory and cognitive functions. Understanding derived from these basic cognitive neuroscience investigations is beginning to be applied to clinically relevant problems. In this article, applications to multiple sclerosis (MS) are reviewed, which address the challenging notion that adaptive cerebral plasticity may have an important influence on the relationship between MS pathology and its clinical expression.
Authors:
A Cifelli; P M Matthews
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Multiple sclerosis (Houndmills, Basingstoke, England)     Volume:  8     ISSN:  1352-4585     ISO Abbreviation:  Mult. Scler.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-07-17     Completed Date:  2003-01-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9509185     Medline TA:  Mult Scler     Country:  England    
Other Details:
Languages:  eng     Pagination:  193-9     Citation Subset:  IM    
Affiliation:
Department of Clinical Neurology, Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, UK.
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MeSH Terms
Descriptor/Qualifier:
Humans
Magnetic Resonance Imaging*
Multiple Sclerosis / pathology,  physiopathology*
Neuronal Plasticity*
Recovery of Function

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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