| Cerebral peritumoral oedema study: Does a single dynamic MR sequence assessing perfusion and permeability can help to differentiate glioblastoma from metastasis? | |
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MedLine Citation:
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PMID: 21334839 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Our purpose was to differentiate glioblastoma from metastasis using a single dynamic MR sequence to assess perfusion and permeability parameters. 24 patients with glioblastoma or cerebral metastasis with peritumoral oedema were recruited and explored with a 3T MR unit. Post processing used DPTools software. Regions of interest were drawn around contrast enhancement to assess relative cerebral blood volume and permeability parameters. Around the contrast enhancement Glioblastoma present high rCBV with modification of the permeability, metastasis present slight modified rCBV without modification of permeability. In conclusion, peritumoral T2 hypersignal exploration associating morphological MR and functional MR parameters can help to differentiate cerebral metastasis from glioblastoma. |
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Authors:
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Pierre Lehmann; Guillaume Saliou; Giovanni de Marco; Pauline Monet; Stoquart-Elsankari Souraya; Alexis Bruniau; Jean Noel Vallée; Denis Ducreux |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-18 |
Journal Detail:
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Title: European journal of radiology Volume: - ISSN: 1872-7727 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Neuroradiology, Amiens University Hospital, 1 Place Victor Pauchet, 80054 Amiens Cedex 1, France; Laboratoire de Neurosciences Fonctionnelles et Pathologies, LFNP-UMR 8160 CNRS CHRU Lille, 59037 Lille Cedex, France; Neuroradiology, AP-HM Timone, 264, rue saint Pierre - 13385 Marseille Cedex 5, France. |
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