| Cerebral perfusion information obtained by dynamic contrast-enhanced phase-shift magnetic resonance imaging: comparison with model-free arterial spin labelling. | |
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MedLine Citation:
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PMID: 20618360 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phase-shift time curves following a bolus injection of gadolinium contrast agent were registered for grey-matter regions and large vessels in 14 subjects. Deconvolving a tissue phase-shift curve with a phase-based arterial input function resulted in a tissue residue function R(t). The peak value of R(t) provided a relative cerebral blood flow (CBF) index, while the area-to-height ratio of R(t) provided quantitative mean transit time (MTT). For comparison, quantitative CBF values in grey matter were acquired using model-free arterial spin labelling (ASL). The phase-based relative CBF estimates showed good linear correlation with ASL-based CBF (r = 0.82). Grey-matter MTT was 4.9 +/- 1.1 s (mean +/- SD). |
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Authors:
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Ronnie Wirestam; Emelie Lindgren; Danielle van Westen; Karin Markenroth Bloch; Freddy Ståhlberg; Linda Knutsson |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-02 |
Journal Detail:
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Title: Clinical physiology and functional imaging Volume: 30 ISSN: 1475-097X ISO Abbreviation: Clin Physiol Funct Imaging Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-10 Completed Date: 2010-12-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137604 Medline TA: Clin Physiol Funct Imaging Country: England |
Other Details:
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Languages: eng Pagination: 375-9 Citation Subset: IM |
Affiliation:
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Department of Medical Radiation Physics, Lund University, Lund, Sweden. ronnie.wirestam@med.lu.se |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Flow Velocity Cerebrovascular Circulation* Contrast Media / diagnostic use* Female Humans Image Interpretation, Computer-Assisted Linear Models Magnetic Resonance Imaging* Male Meglumine / diagnostic use* Middle Aged Models, Cardiovascular Organometallic Compounds / diagnostic use* Predictive Value of Tests Regional Blood Flow Spin Labels* Sweden Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 0/Spin Labels; 0/gadoterate meglumine; 6284-40-8/Meglumine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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