Document Detail


Cerebral perfusion abnormalities in cases of Down syndrome.
MedLine Citation:
PMID:  21317474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A SPECT (single photon emission computed tomography using Tc-99m HMPAO) study of brain with segmental quantitative analysis was conducted to access the cerebral perfusion in cases of Downs syndrome (DS). Varying level of brain hypo-perfusion was documented, probably explaining the neurophysiologic basis of cognitive and neuropsychological deficits, which are not well understood in DS.
Authors:
Sunil Kumar Gupta; B Venkat Ratnam
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian pediatrics     Volume:  48     ISSN:  0974-7559     ISO Abbreviation:  Indian Pediatr     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-02-14     Completed Date:  2011-06-30     Revised Date:  2011-11-21    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  70-1     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Brain / blood supply*,  radionuclide imaging
Cerebrovascular Circulation
Child
Child, Preschool
Down Syndrome / etiology,  radionuclide imaging*
Humans
Perfusion Imaging
Tomography, Emission-Computed, Single-Photon

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