Document Detail

Cerebral palsy due to nonlethal maternal carbon monoxide intoxication.
MedLine Citation:
PMID:  17584908     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Carbon monoxide (CO) poisoning in pregnancy is a relatively rare occurrence, but it can result in fetal mortality and neurologic complications in fetuses who survive to term. CASE: We describe the course of an infant who was acutely exposed to CO at 20 weeks of gestation. CONCLUSIONS: We conclude that despite maternal well-being, CO intoxication at critical periods of human brain development can lead to hypoxic-ischemic lesions in the globus pallidus and that dystonic cerebral palsy may develop in the infant during long-term follow-up.
Füsun Alehan; Ilknur Erol; Ozge Sürmeli Onay
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Birth defects research. Part A, Clinical and molecular teratology     Volume:  79     ISSN:  1542-0752     ISO Abbreviation:  Birth Defects Res. Part A Clin. Mol. Teratol.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-09     Completed Date:  2007-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101155107     Medline TA:  Birth Defects Res A Clin Mol Teratol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  614-6     Citation Subset:  IM    
Copyright Information:
2007 Wiley-Liss, Inc.
Department of Pediatrics, Neurology Division, Baskent University Faculty of Medicine, Ankara, Turkey.
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MeSH Terms
Abnormalities, Drug-Induced / etiology*
Brain / pathology
Carbon Monoxide / adverse effects*
Carbon Monoxide Poisoning*
Cerebral Palsy / chemically induced*,  pathology
Fetal Development / drug effects*
Gestational Age
Infant, Newborn
Inhalation Exposure
Magnetic Resonance Imaging
Maternal Exposure*
Maternal-Fetal Exchange
Reg. No./Substance:
630-08-0/Carbon Monoxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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