Document Detail

Cerebral near-infrared spectroscopy analysis in preterm infants with intraventricular hemorrhage.
MedLine Citation:
PMID:  22254711     Owner:  NLM     Status:  MEDLINE    
Near-infrared spectroscopy (NIRS) for cerebral circulation monitoring has gained popularity in the neonatal intensive care setting, with studies showing the possibility of identifying preterm infants with intraventricular hemorrhage (IVH) by transfer function analysis of arterial blood pressure (BP) and NIRS measures. In this study, we examined a number of NIRS-derived measures in a cohort of preterm infants with IVH (n = 5) and without IVH (n = 12) within 1-3 hours after birth. The IVH infants were found to have significantly higher tissue oxygenation index (TOI), lower fractional tissue oxygen extraction (FTOE) and lower coherence between arterial BP and deoxygenated hemoglobin (HHb) in the very low frequency range (VLF, 0.02-0.04 Hz). Further studies with larger sample size are warranted for a more complete understanding of the clinical utility of these NIRS measures for early identification of IVH infants.
Ying Zhang; Gregory S H Chan; Mark B Tracy; Qim Y Lee; Murray Hinder; Andrey V Savkin; Nigel H Lovell
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-06-12     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1937-40     Citation Subset:  IM    
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MeSH Terms
Cerebral Hemorrhage / blood*,  diagnosis*
Cerebral Ventricles / metabolism*
Hemoglobins / analysis*
Infant, Newborn
Infant, Premature / blood*
Oxygen / blood*
Reproducibility of Results
Sensitivity and Specificity
Spectroscopy, Near-Infrared / methods*
Reg. No./Substance:
0/Hemoglobins; S88TT14065/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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