Document Detail


Cerebral mucormycosis associated with intravenous drug use: three case reports and review.
MedLine Citation:
PMID:  7888545     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We describe three cases of cerebral mucormycosis in intravenous drug users and review 22 previously reported cases. Involvement of the basal ganglia was demonstrated in all but two cases. Seven of the 10 patients tested for antibodies to the human immunodeficiency virus (HIV) were seronegative. Eight of the 25 patients survived and were discharged from the hospital; for 7 of 10 patients, cultures of brain lesions yielded Rhizopus arrhizus. The radiographic findings varied, and in most cases, no or minimal contrast enhancement was seen in the initial computed tomography scans. Although uncommon, the diagnosis of cerebral mucormycosis should be considered when basal ganglia lesions are present in an intravenous drug user, regardless of previous exposure to HIV.
Authors:
R J Hopkins; M Rothman; A Fiore; S E Goldblum
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  19     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-04-17     Completed Date:  1995-04-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1133-7     Citation Subset:  IM; X    
Affiliation:
Department of Medicine, University of Maryland School of Medicine, Baltimore.
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MeSH Terms
Descriptor/Qualifier:
AIDS-Related Opportunistic Infections / diagnosis,  therapy
Adult
Basal Ganglia / microbiology,  pathology
Basal Ganglia Diseases / diagnosis,  etiology*,  microbiology
Fatal Outcome
Female
Humans
Male
Mucormycosis / diagnosis,  etiology*
Rhizopus / isolation & purification
Substance Abuse, Intravenous / complications*
Comments/Corrections
Comment In:
Clin Infect Dis. 1995 Nov;21(5):1352   [PMID:  8589185 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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