Document Detail


Cerebral ischemia detected with diffusion-weighted MR imaging after stent implantation in the carotid artery.
MedLine Citation:
PMID:  11847042     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: Concern regarding the safety of stent implantation in the carotid artery exists because of the risk of cerebral embolization during the procedure. The purpose of this prospective study was to determine the incidence of new areas of cerebral ischemia, as detected by using diffusion-weighted MR imaging after stent implantation in the carotid artery. METHODS: Diffusion-weighted MR imaging of the brain was performed in 67 patients with 70 high-grade stenoses of the carotid artery before and 24 hours after stent implantation. RESULTS: The neurologic status of the patients was unchanged after 69 of 70 procedures. During one procedure, symptomatic cerebral embolization occurred. Diffusion-weighted MR images showed new ipsilateral lesions after stent implantation in 20 patients (29%), including the symptomatic patient, and new contralateral lesions in six patients (9%). Fifty-two of 59 postprocedural lesions occurred in the vascular territory supplied by the treated vessel. The occurrence of new postprocedural ipsilateral lesions was not significantly correlated with patient demographic data, characteristics of the stenoses, or details of the procedure. CONCLUSION: In 29% of the procedures, stent implantation in the carotid artery was associated with new areas of cerebral ischemia, as detected by using diffusion-weighted MR images; these findings indicated the occurrence of cerebral microemboli during such procedures. In all patients except one, the new lesions were clinically silent.
Authors:
Horst J Jaeger; Klaus D Mathias; Elke Hauth; Robert Drescher; H Martin Gissler; Svenja Hennigs; Andreas Christmann
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  23     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-15     Completed Date:  2002-03-26     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  200-7     Citation Subset:  IM    
Affiliation:
Department of Radiology, Staedtische Kliniken Dortmund, University of Witten/Herdecke, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Brain Ischemia / diagnosis*,  etiology*,  physiopathology,  therapy
Carotid Arteries / pathology*
Cerebral Angiography
Diffusion
Female
Humans
Magnetic Resonance Angiography
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Nervous System / physiopathology
Prospective Studies
Stents / adverse effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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