| Cerebral infarcts in full term neonates. | |
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MedLine Citation:
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PMID: 12921302 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral infarcts are an important cause of neonatal convulsions. We report the etiologic factors, and clinical and neuroradiologic findings of four full term neonates who presented with neonatal convulsions and had cerebral infarct. In our patients the risk factors for the cerebral infarct were perinatal asphyxia, sepsis, dehydration and catheter application. All had convulsions as the initial sign of infarct and had cranial imaging which revealed the definitive diagnosis. The patients underwent an extensive evaluation for hereditary causes of cerebral infarct that included anticoagulant factors (Proteins C and S, antithrombin III, antiphospholipid antibodies), factor V Leiden and prothrombin gene mutations, blood and urine amino acid and urine organic acid levels. The results were found to be within normal limits. In conclusion, neonatal convulsions can be the first sign of cerebral infarct. For this reason it seems preferable to include cranial imaging by computed tomography or magnetic resonance imaging (MRI) in the work-up of cases with unexplained neonatal convulsions. |
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Authors:
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Ipek Akman; Eren Ozek; Yüksel Yilmaz; Hülya Bilgen |
Publication Detail:
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Type: Case Reports; In Vitro; Journal Article |
Journal Detail:
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Title: The Turkish journal of pediatrics Volume: 45 ISSN: 0041-4301 ISO Abbreviation: Turk. J. Pediatr. Publication Date: 2003 Apr-Jun |
Date Detail:
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Created Date: 2003-08-18 Completed Date: 2003-11-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417505 Medline TA: Turk J Pediatr Country: Turkey |
Other Details:
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Languages: eng Pagination: 141-7 Citation Subset: IM |
Affiliation:
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Division of Neonatology, Department of Pediatrics, Marmara University Faculty of Medicine, Istanbul, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Infarction*
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etiology,
pathology,
radiography Female Humans Infant, Newborn Magnetic Resonance Imaging Prognosis Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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