Document Detail


Cerebral infarct mimicking glioma in Sjogren's syndrome.
MedLine Citation:
PMID:  12167735     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 50-year-old Chinese woman with a chronic 20-year history of ataxic gait associated with dry eyes and mouth, was admitted to hospital after a single episode of syncope. Magnetic resonance imaging scans showed a large left frontal hypodense lesion suggestive of a glioma. Craniotomy was performed and the lesion excised, with histology showing only infarcted tissue and no malignant cells. Further diagnostic evaluation revealed that the patient had primary Sjogren's syndrome, with demyelinating polyneuropathy. In the absence of risk factors for stroke, it was considered likely that the cerebral infarct was secondary to autoimmune-related vasculitis. Functional neuroimaging, such as magnetic resonance spectroscopy, should be considered in evaluating doubtful or unusual brain lesions in patients with autoimmune disease.
Authors:
M S Koh; K Y C Goh; C Chen; H S Howe
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine     Volume:  8     ISSN:  1024-2708     ISO Abbreviation:  Hong Kong Med J     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-08-08     Completed Date:  2002-11-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9512509     Medline TA:  Hong Kong Med J     Country:  China    
Other Details:
Languages:  eng     Pagination:  292-4     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Singapore General Hospital, Outram Road, Singapore.
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MeSH Terms
Descriptor/Qualifier:
Brain / pathology
Brain Neoplasms / diagnosis*
Cerebral Infarction / diagnosis*,  pathology
Craniotomy
Diagnosis, Differential
Female
Glioma / diagnosis*
Humans
Magnetic Resonance Imaging
Middle Aged
Sjogren's Syndrome / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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