| Cerebral hypoxic ischemia at different cerebral oxygen saturations in piglets: amplitude-integrated EEG study. | |
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MedLine Citation:
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PMID: 19163768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: the objective of present paper was to study the amplitude-integrated EEG (aEEG) in hypoxic ischemic (HI) animal models and to test the reliability of aEEG method when used to monitor cerebral injuries. METHOD: HI animal models were constructed and classified into mild, moderate and severe cerebral oxygen saturation groups according to regional oxygen saturation (rSO(2)) in brains. Then aEEG waveforms were obtained from raw EEG data using digital signal processing. RESULT: aEEG reflected cerebral functions consistently and accurately at different cerebral rSO(2) levels. aEEG waveforms rarely changed in the group of mild HI; they dropped but recovered in moderate HI group; and aEEG maintained very low after HI in the cases when severe HI happened. CONCLUSION: aEEG method could monitor cerebral functions directly, accurately and consistently. It is a reliable tool to continuously evaluate cerebral injuries. |
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Authors:
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Dandan Zhang; Haiyan Ding; Xinlin Hou; Yunfeng Liu; Datian Ye |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference Volume: 2008 ISSN: 1557-170X ISO Abbreviation: Conf Proc IEEE Eng Med Biol Soc Publication Date: 2008 |
Date Detail:
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Created Date: 2009-02-16 Completed Date: 2009-05-11 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 101243413 Medline TA: Conf Proc IEEE Eng Med Biol Soc Country: United States |
Other Details:
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Languages: eng Pagination: 4712-5 Citation Subset: IM |
Affiliation:
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Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China. zhangdd05@mais.tsinghua.edu.cn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms Animals Animals, Newborn Anoxia* Brain Injuries / diagnosis*, physiopathology Cerebrovascular Circulation / physiology* Electrodes Electroencephalography / methods* Hypoxia-Ischemia, Brain / physiopathology* Ischemia / pathology* Models, Theoretical Oxygen / chemistry, metabolism Reproducibility of Results Swine Time Factors |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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