| Cerebral hyperperfusion syndrome. | |
| | |
MedLine Citation:
|
PMID: 16297845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy is characterised by ipsilateral headache, hypertension, seizures, and focal neurological deficits. If not treated properly it can result in severe brain oedema, intracerebral or subarachnoid haemorrhage, and death. Knowledge of CHS among physicians is limited. Most studies report incidences of CHS of 0-3% after carotid endarterectomy. CHS is most common in patients with increases of more than 100% in perfusion compared with baseline after carotid endarterectomy and is rare in patients with increases in perfusion less than 100% compared with baseline. The most important risk factors in CHS are diminished cerebrovascular reserve, postoperative hypertension, and hyperperfusion lasting more than several hours after carotid endarterectomy. Impaired autoregulation as a result of endothelial dysfunction mediated by generation of free oxygen radicals is implicated in the pathogenesis of CHS. Treatment strategies are directed towards regulation of blood pressure and limitation of rises in cerebral perfusion. Complete recovery happens in mild cases, but disability and death can occur in more severe cases. More information about CHS and early institution of adequate treatment are of paramount importance in order to prevent these potentially severe complications. |
| | |
Authors:
|
Walther N K A van Mook; Roger J M W Rennenberg; Geert Willem Schurink; Robert Jan van Oostenbrugge; Werner H Mess; Paul A M Hofman; Peter W de Leeuw |
Related Documents
:
|
1523755 - Effects of vasoactive intestinal peptide, peptide histidine methionine, and neuropeptid... 1266995 - Effect of cervical sympathetic nerve stimulation on canine carotid sinus reflex. 21994335 - Variability among electronic cigarettes in the pressure drop, airflow rate, and aerosol... 4045185 - Reflex control of blood pressure and heart rate by arterial baroreceptors and by cardio... 15850685 - A two-step scenario for hearing assessment with otoacoustic emissions at compensated mi... 9104515 - Haemodynamic changes induced by two i:e ratios: a transoesophageal echocardiographic st... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Lancet neurology Volume: 4 ISSN: 1474-4422 ISO Abbreviation: Lancet Neurol Publication Date: 2005 Dec |
Date Detail:
|
Created Date: 2005-11-21 Completed Date: 2006-01-25 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 101139309 Medline TA: Lancet Neurol Country: England |
Other Details:
|
Languages: eng Pagination: 877-88 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine and Intensive Care, University Hospital Maastricht, Maastricht, Netherlands. wvm@sint.azm.nl |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Algorithms Cerebrovascular Circulation / physiology* Cerebrovascular Disorders / epidemiology, etiology*, physiopathology Endarterectomy, Carotid / adverse effects* Functional Laterality Humans Perfusion / adverse effects* Postoperative Complications Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Drug-induced tremors.
Next Document: Accident prediction model for railway-highway interfaces.