| Cerebral histoplasmosis in the azole era: report of four cases and review. | |
| | |
MedLine Citation:
|
PMID: 12916564 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report four cases of cerebral histoplasmosis and discuss features of six additional cases reported in the medical literature in the past 10 years, when azoles have been available for therapy. Most patients with this disease are immunocompromised or have a history that suggests heavy exposure to Histoplasma capsulatum. Fever and other clinical findings of systemic toxicity caused by disseminated histoplasmosis may be absent; 5 of 10 patients did not manifest these findings. Although the mainstay of treatment for central nervous system histoplasmosis remains amphotericin B, 9 of the 10 patients received itraconazole or fluconazole either as initial therapy or after a course of treatment with amphotericin B. |
| | |
Authors:
|
Michael Saccente; Richard W McDonnell; Larry M Baddour; M Jane Mathis; Robert W Bradsher |
Related Documents
:
|
22333684 - The reliability of suicide statistics: a systematic review. 2817774 - Incontinentia pigmenti: xp breakpoint is not the same in a case of r(x) and in x/autoso... 8587584 - Epididymal histoplasmosis diagnosed by isolation of histoplasma capsulatum from semen. 21214044 - Primary pleural haemangioendothelioma in an italian female patient: a case report and r... 8553794 - Cervical dystonia (spasmodic torticollis). some aspects of the natural history. 3921484 - Leiomyosarcoma of mandible in a sudanese female. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: Southern medical journal Volume: 96 ISSN: 0038-4348 ISO Abbreviation: South. Med. J. Publication Date: 2003 Apr |
Date Detail:
|
Created Date: 2003-08-14 Completed Date: 2003-08-26 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 0404522 Medline TA: South Med J Country: United States |
Other Details:
|
Languages: eng Pagination: 410-6 Citation Subset: AIM; IM |
Affiliation:
|
Division of Infectious Diseases, Department of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA. saccentemichael@uams.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Amphotericin B / therapeutic use* Antifungal Agents / therapeutic use* Fatal Outcome Female Histoplasmosis / diagnosis, drug therapy*, physiopathology Humans Male Middle Aged |
| Chemical | |
Reg. No./Substance:
|
0/Antifungal Agents; 1397-89-3/Amphotericin B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endocarditis due to Staphylococcus aureus after minor dog bite.
Next Document: Understanding and using the implicit association test: I. An improved scoring algorithm.