| Cerebral hemodynamics in patients with moyamoya disease and in patients with atherosclerotic occlusion of the major cerebral arterial trunks. | |
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MedLine Citation:
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PMID: 9409413 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the difference in cerebral hemodynamics between Moyamoya disease and atherosclerotic occlusion of the major cerebral arterial trunks, we measured local cerebral blood flow (CBF) and local CO2 reactivity (CO2R) by xenon-enhanced computed tomography (CT). A total of 11 adult patients with Moyamoya disease (mean age, 39.6 +/- 7.8 years) and eight patients with atherosclerotic occlusion of the major arterial trunks (mean age, 62.4 +/- 15.4 years) were studied. Regions of interest were frontal, temporal and occipital cortex, caudate, putamen and thalamus in each hemisphere. In patients with Moyamoya disease, local CBF values in the internal carotid artery territory (frontal and temporal cortex, caudate, putamen) were significantly higher than those in the occluded side of patients with atherosclerotic occlusion. Local CO2R values in the caudate and putamen were significantly higher than those in the occluded side of patients with atherosclerotic occlusion. These results suggest that the cerebral hemodynamics of Moyamoya disease differ from those of atherosclerotic occlusion of the major cerebral arterial trunks, and may be a result of the abundant collateral circulation through basal 'Moyamoya' vessels. |
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Authors:
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K Obara; Y Fukuuchi; M Kobari; S Watanabe; T Dembo |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: 99 Suppl 2 ISSN: 0303-8467 ISO Abbreviation: Clin Neurol Neurosurg Publication Date: 1997 Oct |
Date Detail:
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Created Date: 1998-02-18 Completed Date: 1998-02-18 Revised Date: 2009-10-14 |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: S86-9 Citation Subset: IM |
Affiliation:
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Department of Neurology, School of Medicine, Keio University, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arteriosclerosis / radiography* Brain / blood supply*, metabolism, radiography* Carbon Dioxide / diagnostic use, pharmacokinetics Cerebral Angiography Cerebral Arteries / radiography* Female Humans Male Middle Aged Moyamoya Disease / radiography* Regional Blood Flow Tomography, X-Ray Computed / methods* Xenon / diagnostic use, pharmacokinetics |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide; 7440-63-3/Xenon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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