Document Detail


Cerebral germinoma with hemiatrophy of the brain: report of three cases.
MedLine Citation:
PMID:  11862514     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The authors report three cases of cerebral germinoma that occurred in young adults with unusual presentation. METHOD: All three patients presented with hemiparesis and were treated at Seoul National University. A histological diagnosis of germinoma was made by a stereotactic biopsy in all three cases. FINDINGS: Magnetic resonance (MR) images showed that their tumors were located in the internal capsule and thalamus, and were associated with ipsilateral cerebral hemisphere and brain stem atrophy. The hemiparesis slowly progressed and this was accompanied by a haemorrhagic cyst in each patient. INTERPRETATION: Clinical diagnosis was not easy because of the unusual clinical presentations and atypical MR imaging findings. It is suggested that cerebral germinoma should be included in the differential diagnosis of a haemorrhagic mass which is associated with cerebral atrophy in the thalamus, basal ganglia, or internal capsule, especially in adolescents or young adults.
Authors:
C H Kim; S H Paek; I A Park; J G Chi; D G Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta neurochirurgica     Volume:  144     ISSN:  0001-6268     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-03-07     Completed Date:  2002-05-07     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  145-50; discussion 150     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Clinical Research Institute, Seoul National University Hospital and College of Medicine, 28 Yongon-dong, Chongno-gu, Seoul 110-744, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Age of Onset
Atrophy
Brain / pathology*
Brain Neoplasms / complications,  pathology*
Cerebral Hemorrhage / etiology
Diagnosis, Differential
Germinoma / complications,  pathology*
Humans
Magnetic Resonance Imaging
Male
Wallerian Degeneration / etiology,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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