| Cerebral embolism with interventional closure of symptomatic patent foramen ovale: an MRI-based study using diffusion-weighted imaging. | |
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MedLine Citation:
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PMID: 17388997 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Paradoxical embolism via patent foramen ovale (PFO) is an important cause of stroke, especially in younger patients. Transcatheter PFO closure is considered to bear a low risk and to be technically feasable with a high primary success rate. There are no data for the rate of procedure-associated silent embolic events. The present study sought to analyze the total number of cerebral ischemic complications with interventional PFO closure. Thirty-five symptomatic PFO patients (15 male, 26-71 years) with cerebral infarctions proven by magnetic resonance imaging (MRI) were examined by diffusion-weighted imaging (DWI) before and after PFO closure. In the MRI examinations following the intervention, new microembolic lesions were found in three of 35 (8.6%) patients. The lesions were located in the right and left thalamus and the left frontoparietal white matter respectively. Two of three infarcts were clinically inapparent, whereas the third patient suffered from a transient right-sided hemihypaesthesia for 12 h. If the prevention of recurrent cerebrovascular events associated with the presence of PFO is necessary, a low frequency of closure associated silent cerebral embolisms was documented after interventional PFO closure. The rate of microembolic events with neurological deficit was 1/35 (approximately 2.8%). |
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Authors:
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U Dorenbeck; B Simon; D Skowasch; C Stüsser; A Gockel; H H Schild; H Urbach; G Bauriedel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: 14 ISSN: 1468-1331 ISO Abbreviation: Eur. J. Neurol. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-03-28 Completed Date: 2007-06-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: England |
Other Details:
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Languages: eng Pagination: 451-4 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Bonn, Bonn, Germany. ulrich.dorenbeck@ukb.uni-bonn.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cardiac Surgical Procedures / adverse effects* Diffusion Magnetic Resonance Imaging Heart Catheterization / adverse effects Heart Septal Defects, Atrial / surgery* Humans Intracranial Embolism / etiology* Male Middle Aged |
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